Table 4.

The GEE results for comparing the mean trend of Edema Volume, BMI, LLIS and its subscales in intervention and control groups.

Dependent variable	Independent Variable	Beta	Standard Error	P-value
Edema volumea	Intercept	606.92	38.44	<0.001
	Time	−50.76	37.20	0.172
	CRP∗time	−92.24	56.10	0.105
	CRS∗time	−135.13	45.31	0.002
BMI	Intercept	28.64	0.89	<0.001
	Time	0.36	0.10	<0.001
	CRP∗time	−1.04	0.17	<0.001
	CRS∗time	−1.32	0.20	<0.001
Total LLIS b	Intercept	0.26	0.08	0.001
	Time	−0.02	0.03	0.362
	CRP∗time	−0.07	0.03	0.012
	CRS∗time	−0.08	0.03	0.004
Physical LLIS b	Intercept	0.30	0.02	<0.001
	Time	−0.12	0.03	<0.001
	CRP∗time	0.03	0.04	0.356
	CRS∗time	0.07	0.04	0.058
Psychosocial LLIS b	Intercept	0.23	0.09	0.009
	Time	0.03	0.03	0.394
	CRP∗time	−0.09	0.04	0.009
	CRS∗time	−0.08	0.04	0.023
Functional LLIS b	Intercept	0.50	0.11	<0.001
	Time	−0.15	0.02	<0.001
	CRP∗time	0.10	0.03	0.003
	CRS∗time	0.10	0.03	0.003

GEE analysis compares the changes of study outcomes in each intervention arm (intervention arm ∗ time interaction) with the control (as the reference group), adjusted for variable factors.

Significant correlations (P < 0.05) are shown in bold text.

Abbreviations: GEE, generalized estimating equations; LLIS, lymphedema life impact scale.

^aAdjusted for % BMI change.

^bAdjusted for baseline BMI, % BMI change, and % edema volume change.