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Fabrication of Escherichia coli (E. coli) generating OMV and assessment of in vitro and in vivo efficacy. (A) E. coli generating OMV displaying HER2-specific affibody and loaded siRNA for cancer therapy. (B) In vitro cell viability evaluation among different groups. (C) Excised tumor tissues of different groups after therapy. Reproduced with permission from [120]. Copyright 2014 American Chemical Society.
