Fig. 7.

In vivo anticancer activity of NPs. (A) 4T1 tumor growth profiles after the intravenous administration of diverse preparations (n = 5). (B) Image of tumors after the last treatment, where a–d were saline, DTX-Sol, PP NPs and PPD NPs, respectively. (C) Tumor burden calculating according to the weight of tumors divided by the average body weight of the mice (n = 5). (D) Body weight evolutions (n = 5), (E) hematological parameters (n = 3), (F) organ index (n = 5) of mice harboring 4T1 tumor xenografts after treatment. Data are the means ± SD, *P < 0.05 and **P < 0.01.