Table 3.
m6A Modification Regulates lncRNA
| m6A Regulator | Associated Cancer | Function | References |
|---|---|---|---|
| Writer | |||
| METTL3 | HCC | enhances LINC00958 stability | 57 |
| METTL3 | NPC | increases lnc FAM225A stability | 58 |
| METTL3 | CRC | increases lnc RP11 nuclear accumulation | 59 |
| Eraser | |||
| ALKBH5 | PAC | inhibits lnc KCNK15-AS1 methylation | 60 |
| ALKBH5 | OST | decreases the m6A modification of lnc PVT1 | 61 |
| ALKBH5 | GC | decreases methylation of the lnc NEAT1 | 62 |
| Reader | |||
| IGF2BP2 | PAC | increases lnc DANCR stability | 63 |
| YTHDF3 | CRC | promotes decay of lnc GAS5 | 64 |