Table 1.
Comparison of baseline characteristics in hospitalized elderly CAP patients with clinical failure and clinical success (n = 3011)
| Characteristics | CF(n = 395) | CS(n = 2616) | p value |
|---|---|---|---|
| Age (years) | 79.3 ± 7.87 | 77.1 ± 7.3 | <0.001 |
| Male sex | 209 (52.9) | 1431 (54.7) | 0.516 |
| Aspiration | 79 (20.0) | 234 (8.9) | <0.001 |
| Long-term bedridden status | 74 (18.7) | 185 (7.1) | <0.001 |
| Underlying conditions | 381 (96.5) | 2344 (89.6) | <0.001 |
| Cardiovascular disease | 268 (67.8) | 1607 (61.4) | 0.014 |
| Hypertension | 215 (54.4) | 1262 (48.2) | 0.023 |
| Ischemic heart disease | 144 (36.5) | 826 (31.6) | 0.057 |
| Congestive heart failure | 46 (11.6) | 150 (5.7) | <0.001 |
| Chronic respiratory disease | 106 (26.8) | 735 (28.1) | 0.631 |
| COPD | 77 (18.5) | 482 (18.4) | 0.627 |
| Bronchiectasis | 17 (4.3) | 273 (10.4) | <0.001 |
| Asthma | 16 (4.1) | 139 (5.3) | 0.330 |
| Cerebral vascular disease | 141 (35.7) | 641 (24.5) | <0.001 |
| Diabetes mellitus | 96 (24.3) | 536 (20.5) | 0.085 |
| Malignancy | 35 (8.9) | 205 (7.8) | 0.485 |
| Chronic renal disease | 37 (9.4) | 114 (4.4) | <0.001 |
| Dementia | 11 (2.8) | 44 (1.7) | 0.154 |
| Chronic liver disease | 5 (1.3) | 33 (1.3) | 1.000 |
| History of CAP within 1 year | 52 (13.2) | 207 (7.9) | 0.001 |
| HCAP | 135 (34.2) | 385 (14.7) | <0.001 |
| Immunocompromise# | 18 (4.6) | 52 (2.0) | 0.004 |
| Numbers of comorbidities | 2.4 ± 1.4 | 1.9 ± 1.3 | <0.001 |
| Severity on hospital admission | |||
| CURB-65a | 2.1 ± 0.9 | 1.5 ± 0.7 | <0.001 |
| PSIb | 118.0 ± 32.2 | 88.9 ± 22.0 | <0.001 |
| ICU admission | 147 (37.2) | 102 (3.9) | <0.001 |
| Outcomes | |||
| Clinical stability on hospital admission | 60 (15.2) | 1015 (46.4) | <0.001 |
| Hospital LOS (days) | 16.4 ± 17.0 | 13.0 ± 8.2 | <0.001 |
| Total cost (RMB, median) | 23,083.1 | 12,287.5 | <0.001 |
Abbreviations: CF Clinical failure; CS Clinical success; COPD Chronic obstructive pulmonary disease; CAP Community acquired pneumonia; HCAP Healthcare-associated pneumonia; PSI Pneumonia severity index; ICU Intensive care unit; LOS Length of stay
#definition seen as Han et al. [15]
a Figure urea nitrogen was missing in 124 cases. n = 2887
b The total number of patients with a complete data of PSI score. n = 1666