Fig. 10.

Comparison between vertebral body insufficiency and pathological fracture. a Non-contrast CT of the thoracic spine shows compression fracture of superior endplate of mid-thoracic vertebral body without sclerotic changes. b Fusion of PET and CT shows mild hypermetabolism associated with the superior endplate fracture, compatible with insufficiency fracture. c Non-contrast CT of the thoracic spine shows multiple sclerotic vertebral bodies with lucent fracture line in one of the vertebral bodies. d Fusion of PET and CT shows intense FDG uptake associated with fracture line as well as adjacent sclerotic vertebral bodies, compatible with pathological fracture