Table 3.

Histaminergic modulation of corticostriatal fEPSP properties across postnatal development^a

	aCSF	Histamine	p
P3–P6
fEPSP amplitude (mV)	0.41 ± 0.10	0.34 ± 0.07	0.56
fEPSP duration (ms)	241.58 ± 39.55	247.41 ± 35.16	0.92
fEPSP rise time (ms)	30.02 ± 9.17	30.68 ± 8.59	0.94
fEPSP decay time (ms)	211.55 ± 30.99	216.74 ± 27.77	0.92
Short-term plasticity (2 vs 1)	1.48 ± 0.18	1.74 ± 0.30	0.48
Short-term plasticity (3 vs 1)	1.55 ± 0.20	1.89 ± 0.37	0.44
Short-term plasticity (4 vs 1)	1.47 ± 0.33	1.86 ± 0.48	0.52
Short-term plasticity (5 vs 1)	1.48 ± 0.38	1.84 ± 0.52	0.58
Short-term plasticity (6 vs 1)	1.52 ± 0.38	1.98 ± 0.59	0.53
P9–P12
fEPSP amplitude (mV)	0.62 ± 0.15	0.50 ± 0.08	0.47
fEPSP duration (ms)	224.74 ± 48.24	225.52 ± 55.01	0.99
fEPSP rise time (ms)	24.22 ± 9.89	26.57 ± 10.94	0.88
fEPSP decay time (ms)	200.52 ± 38.41	198.96 ± 44.26	0.98
Short-term plasticity (2 vs 1)	1.01 ± 0.18	1.03 ± 0.12	0.93
Short-term plasticity (3 vs 1)	0.97 ± 0.21	0.91 ± 0.15	0.82
Short-term plasticity (4 vs 1)	0.93 ± 0.23	0.86 ± 0.20	0.83
Short-term plasticity (5 vs 1)	0.95 ± 0.25	0.87 ± 0.19	0.82
Short-term plasticity (6 vs 1)	0.96 ± 0.28	0.89 ± 0.21	0.83
P21–P35
fEPSP amplitude (mV)	1.74 ± 0.75	1.50 ± 0.65	0.81
fEPSP duration (ms)	196.93 ± 58.46	188.62 ± 51.16	0.92
fEPSP rise time (ms)	18.56 ± 8.99	19.50 ± 9.22	0.94
fEPSP decay time (ms)	178.37 ± 49.69	169.12 ± 42.80	0.89
Short-term plasticity (2 vs 1)	0.92 ± 0.05	1.19 ± 0.21	0.26
Short-term plasticity (3 vs 1)	0.79 ± 0.07	1.15 ± 0.25	0.20
Short-term plasticity (4 vs 1)	0.71 ± 0.09	1.07 ± 0.21	0.17
Short-term plasticity (5 vs 1)	0.70 ± 0.08	0.97 ± 0.17	0.20
Short-term plasticity (6 vs 1)	0.67 ± 0.08	1.03 ± 0.20	0.14

^aData are mean ± SEM; statistical comparisons by Mann–Whitney U test.