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. Author manuscript; available in PMC: 2020 Sep 12.
Published in final edited form as: Lab Chip. 2019 Mar 27;19(7):1193–1204. doi: 10.1039/c8lc00755a

Figure 7. Transcriptome analysis reveals mechanisms of gemcitabine sensitivity.

Figure 7.

Solute carrier family mRNAs are strongly regulated between the 608 and 366 PDAC lines. The magnitude of differential expression of the SLC transporters range roughly 500-fold in either direction. Four SLC transporters known to import gemcitabine are labeled. SLC28A3 is upregulated over 400-fold in PDAC 608 compared to PDAC 366 in the TMES.