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. Author manuscript; available in PMC: 2020 Sep 12.
Published in final edited form as: J Hypertens. 2020 Aug;38(8):1443–1456. doi: 10.1097/HJH.0000000000002438

Table 2.

Medications that may cause falsely-elevated results for plasma and urinary metanephrines due to pharmacodynamic interference

Plasma and urine

Normetanephrine Metanephrine 3-Methoxytyramine

Antidepressants ++ - -

Phenoxybenzamine ++ - -

MAO-inhibitors ++ ++ -

Sympathomimetics + + -

Levodopa - - +++

MAO = monoamine oxidase;

++

clear increase;

+

mild increase;

-

no increase