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. 2020 Sep 9;8:e9903. doi: 10.7717/peerj.9903

Table 2. Outcome measures between groups.

Outcome measures Median (first and third quartiles) U Z p r
Low PCS (<14.5) High PCS (14.5)
WOMAC (0–96 range)
1 week 29 (21 and 45) 50 (41.75 and 65.29) 155 −4.363 .000 .563c
1 month 20.5 (13.75 and 26.5) 34 (23.75 and 53.25) 200 −3.699 .000 .578c
3 months 15 (7.75 and 26) 30 (11.50 and 46.25) 267.5 −2.700 .007 .349b
6 months 9 (5 and 19) 28.5 (8.50 and 39) 210 −3.416 .001 .445b
WOMAC pain (0–20 range)
1 week 5.5 (3 and 7) 9 (7.38 and 11.44) 125.5 −4.820 .000 .622c
1 month 4 (2 and 6) 7 (4.75 and 10.25) 207.5 −3.602 .000 .465b
3 months 3 (1 and 5) 5.5 (2 and 10.25) 296 −2.288 .022 .295a
6 months 2 (1 and 3) 6 (2 and 8.25) 228.5 −3.157 .002 .411b
WOMAC stiffness (0–8 range)
1 week 2.5 (2 and 4) 4 (3 and 5.25) 202.5 −3.737 .000 .482b
1 month 2 (1 and 3) 3.5 (3 and 4.25 236.5 −3.222 .001 .416b
3 months 1.5 (1 and 3) 3 (1 and 4.25) 317.5 −1.999 .046 .258a
6 months 1 (0 and 1.5) 2 (.75 and 4) 269.5 −2.596 .009 .338b
WOMAC disability (0–68 range)
1 week 21.5 (16 and 34.5) 37.20 (30.75 and 50) 178 −4.023 .000 .519c
1 month 15 (9.75 and 19) 23.50 (16.25 and 36) 213.5 −3.501 .000 .452b
3 months 11.5 (4.75 and 18.25) 22 (7.75 and 30) 262 −2.782 .005 .359b
6 months 5 (3.50 and 14) 19 (6.50 and 27.5) 198 −3.601 .000 .469b
EQ–5D–5L (0–1 range)
1 week .608 (.527 and .527) .281 (.076 and .480) 131.5 −4.710 .000 .608c
1 month .728 (.636 and .849) .648 (.354 and .748) 276.5 −2.668 .010 .332b
3 months .849 (.742 and .910) .721 (.590 and .843) 289.5 −2.379 .017 .307b
6 months .910 (.412 and .759) .709 (.562 and .897) 222 −3.258 .001 .424b
4MWT (meters/second)
1 week .599 (.412 and .759) .413 (.309 and .727) 308 −2.100 .036 .271a
1 month .812 (.676 and 1.063) .780 (.553 and 1.002) 390.5 −.880 .379 .114a
3 months 1.127 (.889 and 1.194) .920 (.791 and 1.022) 286.5 −2.417 .016 .312b
6 months 1.226 (.949 and 1.434) 1.041 (.791 and 1.167) 321 −1.728 .084 .225a
30s CST (repetitions)
1 week 6 (2.25 and 9) 0.5 (.00 and 5.25) 255 −2.965 .003 .284a
1 month 9.5 (6 and 12.25) 7 (4.75 and 10) 302 −2.196 .028 .284a
3 months 12 (9 and 14) 9 (6 and 11.25) 258.5 −2.844 .004 .367b
6 months 12 (9 and 15) 12 (9 and 15) 248.5 −2.838 .005 .369b
Active knee flexion (degrees)
1 week 85 (70 and 95) 80 (65 and 90) 376 −1.100 .271 .142a
1 month 102.5 (90 and 110) 100 (90 and 110) 439 −.164 .870 .021
3 months 110 (100 and 116.25) 110 (100 and 116.25) 446.5 −.052 .958 .007
6 months 115 (110 and 122.5) 110 (105 and 125) 403.5 −.482 .630 .063
Active knee extension (degrees)
1 week −10 (−11.25 and −8.75) −10 (−15 and −10) 385.5 −1.043 .279 .135a
1 month −10 (−10 and −5) −10 (−10 and −5) 406 −0.701 .483 .090
3 months −5 (−5 and 0) −5 (−10 and −5) 347 −1.646 .100 .212a
6 months 0 (−5 and 0) −5 (−5 and 0) 310.5 −2.063 .039 .269a
VAS Rest (0–10 range)
1 week 3 (1.375 and 4) 5.75 (4 and 7) 147.5 −4.502 .000 .581c
1 month 2 (.75 and 3.25) 4 (2 and 7) 252.5 −2.948 .003 .381b
3 months 0 (0 and 2) 3.5 (0 and 6) 267.5 −2.824 .005 .365b
6 months 0 (0 and 1.5) 2 (0 and 5) 230.5 −3.255 .001 .424b
VAS Walking (0–10 range)
1 week 3 (1 and 4.125) 6 (4.75 and 8) 151 −4.438 .000 .573c
1 month 2 (1 and 4) 5 (2.75 and 7) 231.5 −3.249 .001 .419b
3 months 3 (0 and 5) 4.5 (2 and 6.25) 319 −1.954 .051 .252a
6 months 2 (0 and 3.25) 3 (1.75 and 6) 258.5 −2.703 .007 .352b
VAS Flexion (0–10 range)
1 week 6 (3 and 7) 8 (7 and 9) 175.5 −4.101 .000 .529c
1 month 3 (2 and 6) 7 (5 and 9) 174.5 −4.096 .000 .529c
3 months 3.25 (.75 and 5) 5 (3 and 8) 244 −3.066 .002 .396b
6 months 2 (0 and 3.5) 3.75 (2 and 6) 251.5 −2.802 .005 .365b

Notes.

PCS
Pain Catastrophizing Scale
WOMAC
Western Ontario and McMaster Osteoarthritis Index
5Q-5D-5L
Euro Quality of Life 5 Dimensions—5 Levels
4MWT
4 Meters Walking Test
30s CST
30-second Chair Stand Test
VAS
Visual Analog Scale
U
Mann Whitney’s U
r
Effect size
a

Small effect size 0.1–0.29.

b

Medium effect size 0.3–0.49.

c

Large effect size > 0.5.