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. 2020 Sep 9;8:e9945. doi: 10.7717/peerj.9945

Table 3. Comparison of clinical characteristics between the discharged and deceased groups.

Variables No. of patients Deceased
(n = 16)
Statistics p-Value
Demographics
Male 61 49 (52.8) 12 (8.2) 4.170d 0.041
Female 58 54 (50.2) 4 (7.8)
Age 119 58.65 ± 1.21 71.81 ± 1.85 −5.948a 0.000
Peak temperature 106 38.54 ± 0.06 38.73 ± 0.16 1.645b 0.100
Dyspnea
Yes 68 54 (58.9) 14 (9.1) 5.598d 0.018
No 51 49 (44.1) 2 (6.9)
Fatigue
Yes 72 61 (62.3) 11 (9.7) 0.526c 0.468
No 47 42(40.7) 5(6.3)
Hematology
WBC, ×10⁹/mL 119 6.49 ± 0.37 8.22 ± 1.22 1.079b 0.281
Neu, ×10⁹/mL 119 5.21 ± 0.34 7.24 ± 1.18 2.060a 0.042
Lym, ×10⁹/mL 119 0.87 ± 0.06 0.58 ± 0.07 −2.551b 0.11
Mon, ×10⁹/mL 118 0.32 ± 0.02 0.35 ± 0.04 1.091a 0.275
NLR 119 8.46 ± 0.83 16.16 ± 3.15 −2.785b 0.005
LMR 119 3.29 ± 0.22 1.64 ± 0.27 2.880a 0.005
Total Tlym, ×106/mL 109 369.89 ± 27.62 168.71 ± 27.53 −3.677b 0.000
CD4+ Tlym, × 106/mL 109 202.67 ± 15.38 115.62 ± 22.70 −2.741b 0.006
CD8+ Tlym, × 106/mL 109 150.17 ± 12.37 51.35 ± 7.92 4.468b 0.000
Th/Ts 109 1.57 ± 0.10 2.45 ± 0.32 2.951b 0.003
CD45, × 106/mL 109 635.82 ± 43.43 346.70 ± 57.66 3.070b 0.002
Biochemical analysis
AST, U/L 119 32.3 ± 1.8 41.9 ± 5.7 −1.831b 0.067
ALT, U/L 119 33.6 ± 3.0 42.1 ± 9.1 −1.266b 0.205
TG, mmol/L 119 1.64 ± 0.07 1.57 ± 0.13 0.055b 0.957
Creatine, μM 119 69.76 ± 2.91 82.25 ± 0.88 −1.611a 0.110
Myo, ng/mL 111 31.80 ± 3.19 109.4 ± 23.93 −10.77b 0.000
CK, U/L 112 100.33 ± 14.21 152.73 ± 30.36 −2.354b 0.019
CK-MB, ng/mL 85 2.37 ± 0.44 2.89 ± 0.58 −2.250b 0.024
Infection indices
LDH, U/L 119 312.95 ± 12.54 481.94 ± 43.23 −3.981b 0.000
CRP, mg/L 119 49.49 ± 3.91 67.37 ± 10.38 −1.753a 0.080
Coagulation function
PCT, ng/mL 114 0.07 ± 0.10 0.20 ± 0.24 −2.610b 0.009
APTT, s 119 35.06 ± 0.62 36.80 ± 0.06 1.176b 0.239
TT, s 118 15.99 ± 0.27 15.72 ± 0.43 −0.830b 0.407
PT, s 119 13.58 ± 0.31 14.19 ± 0.66 −1.068b 0.286
INR 119 1.09 ± 0.03 1.13 ± 0.05 −1.169b 0.242
FIB, g/L 119 4.82 ± 0.85 4.64 ± 0.40 0.651b 0.515
D-Dimer, mg/L 115 1.25 ± 0.29 3.19 ± 1.27 −3.003b 0.003
Blood gas analysis
PH 119 7.43 ± 0.01 7.41 ± 0.04 0.507a 0.619
PCO2, mmHg 118 38.75 ± 0.47 33.80 ± 1.91 2.514a 0.023
PO2, mmHg 119 81.98 ± 3.07 55.06 ± 3.49 −3.837b 0.000
SO2, % 119 93.88 ± 0.47 83.63 ± 4.83 −3.582b 0.029
oxygenation, mmHg 119 282.8 ± 13.9 124.3 ± 10.6 9.072a 0.000

Notes:

a

t-test.

b

Mann–Whitney U test.

c

χ2 test.

d

Continuity Correction.

NLR, neutrophil lymphocyte ratio; LMR, lymphocyte monocyte ratio.