Table 2.
Minimum Inhibitory Concentration (µg/mL) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Name | pPABL048 | Gentamicin | Cefepime | Ceftazidime | Piperacillin-Tazobactam | Meropenem | Aztreonam | Ciprofloxacin | Colistin |
PABL048 | + | >128–ns | 8 | 2 | 64–ns | 8–ns | 32–ns | 32–ns | 0.5 |
PABL048-c1 | - | 4 | 4 | 4 | 16 | 4–ns | 16–ns | 16–ns | 0.5 |
PABL048-c2 | - | 8–ns | 4 | 4 | 16 | 4–ns | 16–ns | 16–ns | 0.5 |
PABL036-GentR | + | >128–ns | 8 | 4 | 32–ns | 8–ns | 16–ns | 32–ns | 0.5 |
PABL036-GentS | - | 4 | 4 | 4 | 16 | 8–ns | 16–ns | 32–ns | 0.5 |
PABL067-GentR | + | >128–ns | 8 | 4 | 64–ns | 8–ns | 32–ns | 32–ns | 0.5 |
PABL067-GentS | - | 4 | 4 | 4 | 16 | 4–ns | 16–ns | 32–ns | 0.5 |
Abbreviations: +, plasmid pPABL048 is present; —, plasmid pPABL048 is absent; c, experimentally cured of pPABL048; GentR, derived from gentamicin-resistant colony; GentS, derived from gentamicin-sensitive colony; ns, nonsusceptible (intermediate and resistant); as defined by the Clinical Laboratory Standards Institute.