Fig. 1. In silico simulation experiments using four cell line or single-cell RNA-Seq datasets.

a Correlations between DEPTH scores and the numbers of cell lines or single cells in the simulated tumor samples. b Correlations between DEPTH scores and the numbers of different cancer types the cell lines originated from or cell lines the single cells belonged to in the simulated tumor samples. ρ, Spearman correlation coefficient. It also applies to the following figures.