Fig. 6. Genes and pathways whose expression alteration or enrichment levels are associated with DEPTH scores in cancer.

a Genes whose expression alteration is strongly associated with DEPTH scores in at least five cancer types (FDR < 0.05, ρ > 0.5), and their associated pathways identified by GSEA³⁴ (FDR < 0.05). b The immune-related pathways highly enriched in low-DEPTH-score versus high-DEPTH-score tumors in at least five cancer types identified by GSEA³⁴ (FDR < 0.05).