Table 1.

Simulation results under proportional MRL models

N	β	censoring rate		Full†		CC (30%)‡		NCC (1-to-1)§
				β1	β2	β1	β2	β1	β2
1000	(0,0)	0.7	Bias	−0.002	−0.002	0.001	0.002	−0.002	−0.001
			SD	0.060	0.105	0.079	0.129	0.072	0.122
			SE	0.061	0.106	0.078	0.136	0.065	0.112
			CP	95.0	94.7	93.9	96.2	92.0	93.2
1000	(0,0)	0.8	Bias	−0.000	−0.001	−0.002	−0.012	−0.001	0.000
			SD	0.071	0.129	0.097	0.156	0.092	0.155
			SE	0.073	0.127	0.091	0.157	0.082	0.143
			CP	95.5	94.2	93.5	94.6	92.7	92.5
1000	(0,0)	0.9	Bias	0.001	−0.009	0.002	0.005	−0.007	−0.001
			SD	0.086	0.153	0.092	0.164	0.114	0.202
			SE	0.086	0.150	0.093	0.162	0.109	0.190
			CP	95.0	94.5	95.8	95.3	93.2	94.4
1000	(0.2,0.2)	0.7	Bias	0.000	−0.001	−0.002	0.002	−0.002	−0.006
			SD	0.048	0.087	0.063	0.104	0.057	0.093
			SE	0.050	0.087	0.060	0.105	0.051	0.088
			CP	95.1	95.3	94.2	95.9	91.7	93.4
1000	(0.2,0.2)	0.8	Bias	0.001	−0.002	0.008	0.002	−0.005	−0.006
			SD	0.057	0.105	0.073	0.125	0.069	0.123
			SE	0.059	0.103	0.073	0.127	0.067	0.116
			CP	95.3	95.4	95.3	95.4	94.2	94.1
1000	(0.2,0.2)	0.9	Bias	−0.004	−0.012	−0.011	−0.013	−0.018	−0.006
			SD	0.079	0.136	0.092	0.154	0.103	0.182
			SE	0.077	0.134	0.088	0.153	0.099	0.174
			CP	94.6	94.8	94.3	94.5	94.2	95.2

SD: sample standard deviation; SE: mean of estimated standard error;

CP: empirical coverage probability of 95% confidence interval;

^†Full-cohort population

^‡Case-Cohort design with 30% random sample from full-cohort population

^§Nested Case-Control design with 1 control for each case