Table 2:
Contraindications to systemic fibrinolysis
Absolute contraindications | Relative contraindications |
---|---|
Active bleeding | Recent bleeding |
Ischemic stroke within 3 months | Current use of anticoagulation |
Prior intracranial hemorrhage | Systolic BP >180 mmHg |
Brain or spinal surgery within 1 month | Diastolic BP >110 mmHg |
Structural cerebrovascular disease or CNS neoplasm | Traumatic or prolonged cardiopulmonary resuscitation |
Suspected aortic dissection | Ischemic stroke more than 3 months prior |
Recent head trauma with fracture or brain injury | Recent non-CNS surgery or invasive procedure |
Abdominal surgery within 7 days | Pericarditis or pericardial fluid |
Pregnancy | |
Low body weight (<60 kg) | |
Age >75 years | |
Diabetic retinopathy |