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. 2020 Mar 31;115(10):1855–1866. doi: 10.1111/add.15013

Table 3.

Associations between lifetime hazardous drinking and incident CVD events and mortality.

CHD incidence Stroke incidence
No. of cases Total no. HR (95% CI) P‐value No. of cases Total no. HR (95% CI) P‐value
Never hazardous drinker 88 1881 1.00 (Ref) 18 1881 1.00
Former early hazardous drinker 41 830 1.10 (0.75, 1.62) 0.615 9 831 1.46 (0.64, 3.31) 0.367
Former later hazardous drinker 24 482 0.91 (0.57, 1.44) 0.686 9 982 1.94 (0.86, 4.38) 0.112
Current hazardous drinker 49 1128 0.85 (0.59, 1.23) 0.399 25 1127 2.75 (1.44, 5.22) 0.002
MI incidence CVD incidence
No. of cases Total no. HR (95% CI) P‐value No. of cases Total no. HR (95% CI) P‐value
Never hazardous drinker 20 1881 1.00 111 1182 1.00
Former early hazardous drinker 14 830 1.50 (0.74, 3.04) 0.266 50 831 1.15 (0.81, 1.62) 0.434
Former later hazardous drinker 6 482 0.92 (0.37, 2.33) 0.864 32 482 1.01 (0.68, 1.51) 0.946
Current hazardous drinker 7 1127 0.46 (0.19, 1.13) 0.091 75 1128 1.13 (0.83, 1.54) 0.445
Total mortality Non‐CVD mortality
No. of cases Total no. HR (95% CI) P‐value No of cases Total no. HR (95% CI) P‐value
Never hazardous drinker 75 1893 1.00 56 1893 1.00
Former early hazardous drinker 28 836 1.14 (0.73, 1.78) 0.573 22 836 1.18 (0.71, 1.96) 0.524
Former later hazardous drinker 26 485 1.48 (0.93, 2.33) 0.095 25 486 1.93 (1.19, 3.14) 0.008
Current hazardous drinker 33 1134 0.94 (0.61, 1.44) 0.771 29 1134 1.10 (0.69, 1.77) 0.687

CVD = cardiovascular disease; CI = confidence interval; HR = hazard ratio; MI = myocardial infarction.