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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Exp Dermatol. 2020 Jul 19;29(8):680–686. doi: 10.1111/exd.14143

Fig. 1.

Fig. 1

Schematic diagram of neural circuits for mechanical and chemical itch. +, - denote excitatory and inhibitory synapses, respectively. GRP, Gastrin Releasing Peptide; GRPR, Gastrin Releasing Peptide Receptor; LTMRs, Low-threshold mechanoreceptors; NK1R, Neurokinin 1 Receptor; NPRA, Natriuretic Peptide Receptor A; NPY, Neuropeptide Y; NPY1R, NPY1 receptor; SST, somatostatin; TLR5, Toll Like Receptor 5.