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. 2020 Sep 10;8:e9882. doi: 10.7717/peerj.9882

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©2020 Andrews et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) IGV visualization of results. At the top of IGV, EBV-1 genome coordinates are shown, followed by ScanFold-Fold predicted base pairs represented as arcs and the location of EBER1 is indicated by the blue cartoon. Base pairs in the reference EBER1 structure correctly predicted by ScanFold-Fold are highlighted in green on the secondary structure in (B). (C) indicates the correctly predicted pairs after refolding the EBER1 sequence using ScanFold-Fold bp with average z-scores < − 2 as constraints.