Table 1.

Results of biochemical work-up undertaken given the history of papillary thyroid cancer and new adrenal mass discovered during evaluation of cerebral lesions.

Laboratory values	Reference range	Patient
Thyroid function
TSH, µIU/mL	0.27–4.20	1.21
Free thyroxine, ng/dL	0.93–1.70	1.58
Thyroglobulin Antibody, IU/mL	<4.0	<1.0
Thyroglobulin, ng/mL	<50.0	<0.5
Neuroendocrine
Chromogranin A, ng/mL	<93	403
Adrenal hormones
Androstenedione, ng/dL
Males >18 years	40–190	19
DHEA, µg/dL
Males >60 years	30–150	31.0
ACTH, pg/mL	7.2–63.3	3.6*
Cortisol, µg/dL	≥2.0	1.3*
Free Normetanephrines, nmol/L	<0.90	12
Free Metanephrines, nmol/L	<0.50	0.39
24-h urine studies
Norepinephrine, µg/24 h	15–80	522
Normetanephrine, µg/24 h		2692
Normotensive	148–560
Hypertensive	<900
Epinephrine, µg/24 h	<21	14
Metanephrine, µg/24 h		244
Normotensive	44–261
Hypertensive	<400
Dopamine, µg/24 h	65–400	101
VMA, mg/24 h	<8	18.9
Renal hormones
Plasma renin activity, ng/mL/h
Na-replete, upright	<0.6–3	2.6
Aldosterone, ng/dL	<21	<4
Cardiovascular
Troponin I (peak), ng/mL	<0.055	0.231
Creatine kinase, U/L	39–308	83
HbA1c, %	<5.7	6.9

*These values were measured 2 days after the patient was initiated on oral dexamethasone therapy for newly discovered cerebral lesions on MRI of the brain.

Abnormal values are presented in bold.

ACTH, adrenocorticotrophic hormone; DHEA, DHEA sulfate; HbA1C, glycosylated hemoglobin; TSH, thyroid stimulating hormone; VMA, vanillylmandelic acid.