Table 1.

Characteristics of SDHX variant positive patients.

Characteristics	Total (n)	With PPGL	No PPGL	Age (years) at first PPGL diagnosis range (median)
Females, n	30	14	16	17–65 (40.5)
Males, n	29	10	19	12–73 (46.5)
Total, n	59	24	35	12–73 (42.5)
Genetic variants	SDHA	SDHB	SDHC	SDHD
Total (n)	2	51	4	2
Patients with PPGL diagnosis, n	1	17	4	1
PGL, n	1	13	4	0
PCC, n	0	4	0	1
RCC, n	0	2	0	1
Patients, n	1	7	2	2
Clinical symptoms reported at PPGL diagnosis, n	0	8	3	0

A patient may display both a phaeochromocytoma and a paraganglioma or a renal cell carcinoma (RCC), therefore the total n is larger than total number of patients with PPGLs.

PCC, phaeochromocytoma; PGL, paraganglioma; PPGL, phaeochromocytoma and paraganglioma; SDHX, succinate dehydrogenase genetic variants.