Table 3.

Selected genes showing substantial overlap in our study.

Promoter	Associated with the same-day levels of a	Associated with the mean of yearly dichotomized levels of a	Overlap with gene-chemical interactions listed by CTDb	In core networkb	Comments
BAALC	BPA	BPA, BP-3,	BPA	Yes	Mainly expressed in brain. Mediates PTH action on bone (45)
CLDN9		TCS, 2,4-DCP	TCS	No	Mainly expressed in brain. Enriched in GnRH neurons (46)
DTX1	Σphth.m	Σphth.m	Σphth.m	No	Ubiquitin ligase involved in Notch signalling
FAM71F1	Σphth.m	TCS, 2,4-DCP, Σphth.m	Σphth.m	No	Uniquely expressed in testis. Related to azoospermia (47)
FAM83A		BPA, 2,4-DCP	BPA	No	Highly expressed in vagina and oesophagus
FBXO47	BPA, BP-3	BPA	BPA	No	Uniquely expressed in testis. Involved in meiosis (48)
HES6	Σphth.m	Σphth.m	Σphth.m	No	Highly expressed in brain and testis. Involved in neurogenesis (49)
PNOC		TCS, BPA	TCS	Yes	Induced in theca cells by hCG administration (50)
SLC38A4	TCS	TCS	TCS	No	System A amino acid transporter, highly expressed in liver
SLC45A4	Σphth.m	Σphth.m	Σphth.m	No	Involved in cognitive functions (51)
SOX10	Σphth.m	Σphth.m	Σphth.m	Yes	Involved in Kallmann syndrome (52) and hypogonadotropic hypogonadism (53)
TAPBP	BPA, Σphth.m	BPA, BP-3	BPA	No	MHC class I antigen-processing
TRIP6	Σphth.m	BP-3, Σphth.m	Σphth.m	Yes	Induced in testicular Leydig cells during puberty (12)

^aSee Fig. 2 for further details; ^bSee Fig. 3 for further details.