Table 5.

Clinical correlation between changes of serum Gpnmb levels, and clinical and biochemical variables after treatment.

Variables	β	P-value	Multiple adjusted P-valuea
BMI (kg/m2)	–0.031	0.844	0.543
Waist circumference (cm)	–0.052	0.741	0.845
BMR (%)	0.477	0.001	0.002
Systolic BP (mmHg)	0.214	0.175	0.145
Diastolic BP (mmHg)	0.024	0.881	0.809
Total cholesterol (mmol/L)	0.253	0.185	0.422
Total triglycerides (mmol/L)	0.006	0.977	0.455
LDL-c (mmol/L)	0.327	0.084	0.128
HDL-c (mmol/L)	–0.051	0.791	0.492
Fasting glucose (mmol/L)	0.083	0.668	0.812
HOMA-IR	0.272	0.154	0.288
ALT (U/L)	0.111	0.553	0.755
AST (U/L)	0.207	0.263	0.329
Free T3 (pmol/L)	0.339	0.028	0.006
Free T4 (pmol/L)	0.316	0.042	0.025
TSH (mIU/L)	–0.079	0.622	0.901
TRAb (IU/L)	0.150	0.348	0.552
TGAb (IU/mL)	–0.091	0.598	0.688
TPOAb (IU/mL)	–0.023	0.891	0.894

^aAdjusted for age, gender, smoking, and BMI before treatment.

BMR, basal metabolic rate; BP, blood pressure; LDL-c, low density lipoprotein cholesterol; HDL-c, high density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; ALT, alanine aminotransferase; AST, aspartate aminotransferase; T3, triiodothyronine; T4, thyroxine; TSH, thyroid stimulating hormone; TPOAb, thyroid peroxide antibody; TGAb, thyroglobulin antibody; TRAb, thyrotropin receptor antibody.