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. 2020 Aug 31;8:765. doi: 10.3389/fcell.2020.00765

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Copyright © 2020 Zhou, Yu, Zhao, Xie, Yang and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Oxygen-dependent pathway of plasmalogens biosynthesis in animals. The enzymes involved in the indicated steps: FAS, fatty acid synthase; ACS, acyl-CoA synthase; FAR1/2, fatty acyl-CoA reductase 1 or 2; DHAP-AT, DHAP acyltransferase; ADHAP-S, alkyl-DHAP synthase; AADHAP-R, NADPH:alkyl-DHAP oxidoreductase; AAG3P-AT, acyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphate acyltransferase; PH, 1-alkyl-2-acyl-sn-glycero-3-phosphate phosphohydrolase; E-PT, CDP-ethanolamine:1-alkyl-2-acyl-sn-glycerol ethanolamine phosphotransferase; TMEM189 homologs, plasmanylethanolamine desaturases.