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. 2020 Aug 31;8:871. doi: 10.3389/fcell.2020.00871

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Copyright © 2020 Xu, Xing, Wu, Chen and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pyroptosis was related with disk degeneration. (A) Protein expression levels of Cleaved caspase–1, NT–GSDMD, IL–1β, and IL–18 in the nucleus pulposus (NP) of healthy donors and IDD patients were measured by western blotting analysis. (B) Quantification of the protein expression levels in each group. Data represent mean ± SD; ^∗∗p < 0.01.