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(A) Laser scanning confocal microscopy images of PC3cells treated with DOX, Zn-BP-PEG/D, Zn-BP-P-Apt/D, Zn-BP-P-Apt/D with free Apt added, and the incubation time was 2 h. (B) The cell viabilities of PC3 cells incubated with various concentrations of BP, BP-PEG, and BP-P-Apt with NIR laser irradiation. (C) In vitro cytotoxicity of BP, BP-P, and BP-P-Apt tested by MTT assay (808 nm, 1 W cm–2, 10 min, **P < 0.01).
