Table S3. The detailed causes of heart failure events in statin hyporesponders and responders.

Age (years)	Sex	LVEF (%)	Factors triggering HF hospitalization
Statin hyporesponders
79	Male	39	High blood pressure
60	Male	40	High blood pressure
81	Female	48	High blood pressure
79	Male	40	Excessive salt/fluid intake
72	Male	60	Excessive salt/fluid intake
65	Male	32	Excessive salt/fluid intake
81	Female	53	ACS
74	Male	23	Drug (NSAIDs)
53	Male	49	Infection
Statin responders
82	Female	45	High blood pressure
69	Male	16	Excessive salt/fluid intake
45	Male	45	Excessive salt/fluid intake
80	Female	48	Excessive salt/fluid intake
57	Male	50	Excessive salt/fluid intake
82	Female	54	Arrhythmia
72	Female	30	Arrhythmia
59	Male	25	Infection
59	Male	37	Infection
79	Female	45	Anemia
71	Male	43	COPD
47	Male	45	Non-adherence of medication
66	Male	31	Sleep apnea syndrome
65	Male	30	Unknown
80	Female	34	Unknown

LVEF, left ventricular ejection fraction; ACS, acute coronary syndrome; COPD, chronic obstructive pulmonary disease; HF, heart failure; NSAIDs, non-steroidal anti-inflammatory drugs.