Figure 2.

A male patient with a mixed echogenicity atherosclerotic plaque of the internal carotid artery. An example of a surface irregularity quantification software using colour Doppler image (A). Note the delineation of plaque surface with a red line and the outer vascular wall with a blue line. Parts of the lumen are not filled with blood flow signals (asterisk), while parts of the plaque surface may be obscured by overwriting artifact. Same software using a CEUS image (B), where the lumen is fully filled with microbubbles and the plaque surface can be better appreciated and delineated. CEUS, contrast-enhanced ultrasound.