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. 2020 Aug 31;11:1993. doi: 10.3389/fmicb.2020.01993

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Copyright © 2020 Crestani, Forde and Zadoks.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Approximately-maximum-likelihood phylogenetic tree of 266 complete prophages identified in group B Streptococcus (GBS) in this study and 22 prophages identified by van der Mee-Marquet et al. (2018). In most cases, full-prophage phylogenetic clusters are concordant with insertion sites and their corresponding integrase types or subtypes (GBS2, GBS3, GBS4, GBS9, GBS11, blue to green branches), with smaller clusters (GBS1, GBS5, GBS8, GBS10, GBS12, black branches) embedded in the larger ones. Some mismatches between prophages and their integrase type or insertion site and major clusters were identified (red branches), which is suggestive of integrase switching events. Tree was rooted at midpoint. NA, not applicable.