Table 3.
Renal function at baseline, 3, 6 and 12 months following renal IrAE
| n | Renal function | SD | p-value in relation to baseline | |
|---|---|---|---|---|
| Baseline Creatinine (μmol/L) | 23 | 89.8 | 18.5 | N/A |
| Baseline eGFR (mL/min/1.73m2) | 73 | 15 | N/A | |
| Peak Creatinine (μmol/L) | 23 | 336.5 | 285 | p = <0.001 |
| Peak eGFR (mL/min/1.73m2) | 24 | 12.4 | p = <0.001 | |
| Creatinine at 3m (μmol/L) | 21 | 127.4 | 35.1 | p = <0.001 |
| eGFR at 3m (mL/min/1.73m2) | 54 | 17.9 | p = <0.001 | |
| Creatinine at 6m (μmol/L) | 16 | 132 | 63.8 | p = 0.002 |
| eGFR at 6m (mL/min/1.73m2) | 54 | 22.7 | p = 0.002 | |
| Creatinine at 12m (μmol/L) | 11 | 107.5 | 20.9 | p = 0.009 |
| eGFR at 12m (mL/min/1.73m2) | 63 | 18.1 | p = 0.068 |
eGFR – estimated glomerular filtration rate. N/A – not available. m – month