Table 3.
Results of exploratory analyses estimating the difference between intervention and standard of care arms in change from baseline to 6 -months of key outcome variablesa
| Adjusted for baseline value of outcome | Adjusted for baseline value of outcome, wave, and site | |||
|---|---|---|---|---|
| Outcome | Estimated effect (95% CI) | ICC (95% CI) | Estimated effect (95% CI) | ICC (95% CI) |
| Change in PHQ-9 Score | −0.50 (− 2.08, 1.07) | 0.067 (− 0.142, 0.276) | −0.60 (− 2.67, 1.47) | 0.248 (− 0.142, 0.639) |
|
Change in SDQ Total Difficulties Score |
− 0.60 (− 2.18, 0.99) | < 0.001 (< 0.001, < 0.001) | −0.88 (−3.22, 1.47) | 0.257 (− 0.168, 0.682) |
| Change in UCLA Trauma Score | 0.03 (− 2.39, 2.45) | 0.023 (− 0.145, 0.191) | −0.03 (− 2.38, 2.32) | 0.025 (− 0.168, 0.217) |
| Change in Total Stigma Score | 2.13 (0.12, 4.14) | 0.069 (− 0.166, 0.304) | 2.11 (0.25, 3.98) | < 0.001 (< 0.001, < 0.001) |
| Change in Internal Stigma Score | 0.75 (− 0.13, 1.63) | 0.084 (− 0.144, 0.311) | 0.80 (− 0.12, 1.71) | 0.089 (− 0.219, 0.397) |
| Change in External Stigma Score | 1.53 (0.09, 2.97) | < 0.001 (< 0.001, < 0.001) | 1.55 (0.09, 3.02) | < 0.001 (< 0.001, < 0.001) |
|
Change in Self-Reported Adherence Score |
6.73 (1.05, 12.41) | 0.052 (− 0.126, 0.230) | 7.29 (2.24, 12.33) | < 0.001 (< 0.001, < 0.001) |
|
Change in Standardized hair concentration |
0.12 (− 0.55, 0.79) | < 0.001 (< 0.001, < 0.001) | 0.17 (− 0.52, 0.85) | < 0.001 (< 0.001, < 0.001) |
| Change in Log (Viral Load) | −0.81 (− 1.65, 0.02) | < 0.001 (< 0.001, < 0.001) | −0.84 (− 1.69, 0.01) | < 0.001 (< 0.001, < 0.001) |
a Negative value favors the intervention except for adherence where a positive value signifies improved adherence. Abbreviations: CI = Confidence Interval; ICC = Intracluster correlation