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. 2020 Sep 7;21:100. doi: 10.1186/s12863-020-00911-w

Table 4.

Total number of LA dogs DNA tested for PRA4, showing genotypes and allele frequencies of the LINE-1 insertion

Genotypea
Cohort
PRA4 −/− PRA4 −/+ PRA4 +/+ Total Allele frequency
Across 22 countries 6 170 735 911 0.1
UK only 4 107 457 568 0.1

aThe wild type allele is represented by ‘+’ and the mutant allele by ‘-‘