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. 2020 Sep 7;8:158. doi: 10.1186/s40478-020-01028-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Electrophysiological analysis of DPR expressing larvae. a Excitatory junction potential (EJP) amplitude, b input resistance (Ri), c mini-EJP (mEJP) amplitutde, d mEJP frequency and e Quantal Content measured at muscle 6 (hemi-segment A3/4) of third instar wandering larvae pan-neuronally expressing (nSyb-Gal4) DPRs or an mCD8-GFP control. f representative traces showing evoked (EJP) (top traces) and spontaneous (mEJP) (bottom traces) responses in control (mCD8-GFP) and AP1000 larvae. n’s are shown on each graph. Recordings were made from at least 5 animals (N = 5) taken from at least 3 independent crosses per genotype