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. 2020 Sep 7;148:e198. doi: 10.1017/S0950268820002034

Table 2.

Comparison of Cox proportional HR in relation to the risk of death

n HR 95% CI P
Age
Up to 50 years old 27 932 1.00
51–67 years old 25 747 1.74 1.67–1.82 <0.001
68 years old or more 26 444 2.77 2.66–2.88 <0.001
Sex
Male 45 926 1.01 0.98–1.03 0.668
Female 34 176 1.00
Race
White or Yellow 24 091 1.00
Black or mixed 26 614 1.54 1.49–1.59 <0.001
Level of education
Higher education 5223 1.00
Intermediate/elementary education 8954 1.49 1.36–1.62 <0.001
Low education 10 391 2.23 2.06–2.42 <0.001
Illiterate 1630 3.29 2.95–3.66 <0.001
Zone
Urban 68 418 1.00
Rural 1864 1.26 1.16–1.38 <0.001
Influenza-like outbreak
Yes 19 609 1.18 1.14–1.22 <0.001
No 35 911 1.00
Hospital-acquired infection
Yes 2143 1.07 1.00–1.15 0.044
No 52 180 1.00
Fever
Yes 58 977 0.79 0.77–0.83 <0.001
No 13 132 1.00
Cough
Yes 61 368 0.79 0.76–0.82 <0.001
No 10 817 1.00
Throat
Yes 17 084 0.88 0.85–0.91 <0.001
No 40 740 1.00
Dyspnoea (shortness of breath)
Yes 55 650 1.46 1.40–1.53 <0.001
No 15 218 1.00
Respiratory distress
Yes 46 460 1.48 1.43–1.54 <0.001
No 19 326 1.00
O2 <95% saturation
Yes 44 351 1.74 1.67–1.81 <0.001
No 21 198 1.00
Diarrhoea
Yes 10 881 0.86 0.82–0.90 <0.001
No 45 191 1.00
Vomit
Yes 6128 0.93 0.88–0.98 0.007
No 48 436 1.00
Cardiopathy
Yes 25 160 1.18 1.13–1.22 <0.001
No 12 619 1.00
Haematological
Yes 759 1.03 0.91–1.16 0.629
No 25 487 1.00
Down's syndrome
Yes 200 1.51 1.20–1.90 <0.001
No 25 911 1.00
Hepatic
Yes 680 1.13 1.01–1.26 0.042
No 25 372 1.00
Asthma
Yes 2238 0.66 0.61–0.73 <0.001
No 24 492 1.00
Diabetes
Yes 18 872 1.19 1.14–1.23 <0.001
No 15 655 1.00
Neurological
Yes 3007 1.31 1.24–1.39 <0.001
No 24 212 1.00
Pneumopathy
Yes 2935 1.11 1.05–1.18 <0.001
No 24 148 1.00
Immunodepression
Yes 2405 0.93 0.87–1.00 0.063
No 24 237 1.00
Kidney disease
Yes 3258 1.25 1.19–1.32 <0.001
No 23 729 1.00
BMI
Normal 17 1.00
Overweight 139 1.18 0.53–2.61 0.675
Obesity I 1227 1.00 0.47–2.12 0.990
Obesity II 616 1.16 0.54–2.45 0.706
Obesity III 475 1.27 0.59–2.70 0.539
Vaccine
Yes 9914 1.01 0.97–1.07 0.532
No 21 723 1.00
Anti-viral
Yes 26 461 0.97 0.94–1.00 0.076
No 34 881 1.00
Antiviral type
Oseltamivir 23 906 1.00
Zanamivir 114 1.13 0.81–1.57 0.473
Other 910 0.95 0.82–1.10 0.491
ICU
Yes 24 284 1.38 1.34–1.43 <0.001
No 40 834 1.00
Ventilatory support
Yes, invasive 23 638 2.94 2.81–3.07 <0.001
Yes, not invasive 27 900 1.59 1.52–1.66 <0.001
No 14 806 1.00
X-ray
Normal 2173 1.00
Infiltrate interstitial 16 003 1.42 1.28–1.57 <0.001
Consolidated 2277 1.42 1.26–1.61 <0.001
Mixed 2723 1.42 1.26–1.59 <0.001
ICU length of stay
Up to 8 days 9452 9.15 8.73–9.60 <0.001
>8 days 7588 1.00