Figure 2.

SWE Occludes w-Pot

(A) Schematic of whisker deprivation.

(B) Schematic of thalamo-cortical circuits. L2/3 pyramidal neurons are recorded in the principal barrel-related column upon deflection of the PW. Depth of recorded cells is indicated.

(C) Time course of averaged PSP peak amplitude before and after RWS in FEW (n = 7 cells) and SWE (n = 7 cells) mice.

(D) Time course of averaged PSP amplitude normalized to baseline.

(E) Left: mean (± SEM) amplitude before (baseline) and after RWS. Error bars, sem; black lines between bars, pairs. Right: mean (± SEM) amplitude normalized to baseline. Triangles, individual cells. ns, not significant.

(F) Median (± interquartile range) of plateau strength (FWE, n = 20 cells; SWE, n = 13 cells).

(G) Correlation between normalized plateau strength and the level of RWS-induced PSP peak potentiation in FWE (light blue) and SWE (dark blue) mice.