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. 2020 Mar 28;43(9):zsaa053. doi: 10.1093/sleep/zsaa053

Figure 5.

Figure 5.

Example and group responses to sustained application of taltirelin at the hypoglossal motoneuron pool. (A) Example representative trace showing the sustained increase in tongue EMG activity with sustained application of taltirelin (1 μM) microperfused into the hypoglossal motoneuron pool. The group data show the effects of sustained application of taltirelin on within-breath phasic (B) and tonic tongue muscle activities (C), diaphragm amplitude (D), and respiratory rate (E). The graphs show individual data derived from each taltirelin experiment in each rat (n = 5 for these separate prolonged 2-h intervention with 1 μM taltirelin, and each symbol represents the mean ± SEM from each animal in protocol 1c) superimposed on the group mean data (vertical bars + SEM). The symbol * indicates p < 0.05 for taltirelin versus the baseline ACSF controls (i.e. [taltirelin] of 0 μM); AU, arbitrary units. See text for further details.