Table 1.
Subpopulation | Outcome | Material sources | Donor age | Reference |
---|---|---|---|---|
CD9+CD90+CD166+ | The potential for osteochondral differentiation | Patients with end-stage OA who underwent total knee joint replacement | 55–82 | Fickert et al. [49] |
CD271+CD90+ | The potential for chondrogenic differentiation | Patients with total knee arthroplasty surgery | N/A | Ogata et al. [51] |
CD73+CD90−/CD73+CD90+ | CD73+CD90− cells can form cartilage only under the stimulation of TGFβ-1; the CD73+CD90+ MSCs subgroup needs to be stimulated by BMP2 and TGFβ-1 | Patients with advanced clinical OA who underwent total knee replacement | 50–80 | Sivasubramaniyan et al. [30] |
SM-MSCs in surface, interstitial and perivascular area | Higher proliferation and chondrogenic potential of MSCs in perivascular area | The knees of patients with osteoarthritis during total knee arthroplasty | 59–85 | Mizuno et al. [14] |
SM-MSCs in the paralabral synovium and the cotyloid fossa synovium | MSCs from the cotyloid fossa synovium have higher proliferation and differentiation potential than do those from the paralabral synovium | Patients with femoroacetabular impingement syndrome but excluded osteoarthritis and inflammatory diseases | 19–64 | Murata et al. [52] |
SM-MSCs in the cotyloid fossa area from the knee and hip | Adipogenesis and osteogenesis potentials of MSCs from the knees are superior to those of MSCs from the hips in the same donor | Patients underwent knee and hip arthroscopic surgeries | 25–64 | Hatakeyama et al. [54] |
N/A not applicable