Skip to main content
. 2020 Aug 6;21(13):903–917. doi: 10.2217/pgs-2020-0045

Table 4. . Results of three case–control association tests.

(A) Genotype test
Rank SNP Gene Chr Location Stat p0 p-value
1 rs3136541 GAL 11 Intronic 11.815 0.0028 0.2457
2 rs2271933 HCRTR1 1 Missense variant 9.1702 0.0081 0.6628
3 s33933482 AVPR1B 1 3′-UTR 9.0174 0.0127 0.6938
4 rs1893679 GAL 11 2KB upstream 8.7719 0.013 0.7298
5 rs4518200 NPY1R 4 Intronic 7.3525 0.0457 0.9231
6 rs973002 CRHR2 7 Intronic 7.1004 0.0335 0.9420
7 rs2270007 CRHR2 7 Intronic 7.0992 0.0337 0.9421
8 rs1715747 CRHBP 5 Intronic 6.6137 0.0345 0.9721
9 rs4691075 NPY1R 4 Intronic 6.2724 0.0459 0.9848
10 rs4691910 NPY1R 4 Intronic 6.2724 0.0459 0.9848
(B) F-test
Rank SNP Gene Chr Location Stat p0 p-value
1 rs3136541 GAL 11 Intronic 10.4347 0.0021 0.1668
2 s33933482 AVPR1B 1 3′-UTR 8.8989 0.0060 0.3495
3 rs1893679 GAL 11 2KB upstream 8.7190 0.0095 0.3755
4 rs1715747 CRHBP 5 Intronic 6.6137 0.0372 0.7865
5 rs4518200 NPY1R 4 Intronic 6.4694 0.0266 0.8092
6 rs4691075 NPY1R 4 Intronic 6.0371 0.0386 0.8747
7 rs4691910 NPY1R 4 Intronic 6.0371 0.0386 0.8747
8 rs1500 CRHBP 5 Noncoding transcript 5.7612 0.0586 0.9102
9 rs2271933 HCRTR1 1 Missense variant 5.7603 0.0293 0.9105
10 rs1056526 HCRTR1 1 Synonymous 5.1361 0.0561 0.9690
(C) Maximum test
Rank SNP Gene Chr Location Stat p0 p-value
1 rs3136541 GAL 11 Intronic 11.5906 0.0017 0.1180
2 s33933482 AVPR1B 1 3′-UTR 8.6916 0.0063 0.4829
3 rs1893679 GAL 11 2KB upstream 8.6124 0.0082 0.4902
4 rs2270007 CRHR2 7 Intronic 7.0954 0.0189 0.7783
5 rs973002 CRHR2 7 Intronic 7.0589 0.0223 0.7842
6 rs1715747 CRHBP 5 Intronic 6.4569 0.0234 0.8760
7 rs2271933 HCRTR1 1 Missense variant 5.7153 0.0347 0.9565
8 rs17339455 NR3C1 5 Intronic 5.6543 0.0491 0.9612
9 rs1500 CRHBP 5 Noncoding transcript 5.6251 0.0371 0.9631
10 rs1056526 HCRTR1 1 Synonymous 4.9800 0.0510 0.9880

SNPs are listed by Stat in descending order. Bold terms indicates p < 0.50.

Chr: Chromosome number; MAF: Minor allelic frequency; p0: Nominal significance level; Stat: Test statistic.