Table 4. . Results of three case–control association tests.
(A) Genotype test | |||||||
---|---|---|---|---|---|---|---|
Rank | SNP | Gene | Chr | Location | Stat | p0 | p-value |
1 | rs3136541 | GAL | 11 | Intronic | 11.815 | 0.0028 | 0.2457 |
2 | rs2271933 | HCRTR1 | 1 | Missense variant | 9.1702 | 0.0081 | 0.6628 |
3 | s33933482 | AVPR1B | 1 | 3′-UTR | 9.0174 | 0.0127 | 0.6938 |
4 | rs1893679 | GAL | 11 | 2KB upstream | 8.7719 | 0.013 | 0.7298 |
5 | rs4518200 | NPY1R | 4 | Intronic | 7.3525 | 0.0457 | 0.9231 |
6 | rs973002 | CRHR2 | 7 | Intronic | 7.1004 | 0.0335 | 0.9420 |
7 | rs2270007 | CRHR2 | 7 | Intronic | 7.0992 | 0.0337 | 0.9421 |
8 | rs1715747 | CRHBP | 5 | Intronic | 6.6137 | 0.0345 | 0.9721 |
9 | rs4691075 | NPY1R | 4 | Intronic | 6.2724 | 0.0459 | 0.9848 |
10 | rs4691910 | NPY1R | 4 | Intronic | 6.2724 | 0.0459 | 0.9848 |
(B) F-test | |||||||
Rank | SNP | Gene | Chr | Location | Stat | p0 | p-value |
1 | rs3136541 | GAL | 11 | Intronic | 10.4347 | 0.0021 | 0.1668 |
2 | s33933482 | AVPR1B | 1 | 3′-UTR | 8.8989 | 0.0060 | 0.3495 |
3 | rs1893679 | GAL | 11 | 2KB upstream | 8.7190 | 0.0095 | 0.3755 |
4 | rs1715747 | CRHBP | 5 | Intronic | 6.6137 | 0.0372 | 0.7865 |
5 | rs4518200 | NPY1R | 4 | Intronic | 6.4694 | 0.0266 | 0.8092 |
6 | rs4691075 | NPY1R | 4 | Intronic | 6.0371 | 0.0386 | 0.8747 |
7 | rs4691910 | NPY1R | 4 | Intronic | 6.0371 | 0.0386 | 0.8747 |
8 | rs1500 | CRHBP | 5 | Noncoding transcript | 5.7612 | 0.0586 | 0.9102 |
9 | rs2271933 | HCRTR1 | 1 | Missense variant | 5.7603 | 0.0293 | 0.9105 |
10 | rs1056526 | HCRTR1 | 1 | Synonymous | 5.1361 | 0.0561 | 0.9690 |
(C) Maximum test | |||||||
Rank | SNP | Gene | Chr | Location | Stat | p0 | p-value |
1 | rs3136541 | GAL | 11 | Intronic | 11.5906 | 0.0017 | 0.1180 |
2 | s33933482 | AVPR1B | 1 | 3′-UTR | 8.6916 | 0.0063 | 0.4829 |
3 | rs1893679 | GAL | 11 | 2KB upstream | 8.6124 | 0.0082 | 0.4902 |
4 | rs2270007 | CRHR2 | 7 | Intronic | 7.0954 | 0.0189 | 0.7783 |
5 | rs973002 | CRHR2 | 7 | Intronic | 7.0589 | 0.0223 | 0.7842 |
6 | rs1715747 | CRHBP | 5 | Intronic | 6.4569 | 0.0234 | 0.8760 |
7 | rs2271933 | HCRTR1 | 1 | Missense variant | 5.7153 | 0.0347 | 0.9565 |
8 | rs17339455 | NR3C1 | 5 | Intronic | 5.6543 | 0.0491 | 0.9612 |
9 | rs1500 | CRHBP | 5 | Noncoding transcript | 5.6251 | 0.0371 | 0.9631 |
10 | rs1056526 | HCRTR1 | 1 | Synonymous | 4.9800 | 0.0510 | 0.9880 |
SNPs are listed by Stat in descending order. Bold terms indicates p < 0.50.
Chr: Chromosome number; MAF: Minor allelic frequency; p0: Nominal significance level; Stat: Test statistic.