Table 1.
General, maternal and infant factors for infants with early onset sepsis during the NePeriQIPa trial, by antibiotic treatment group; Guideline (n = 1172) and Non-Guideline (n = 354)
| Background characteristic | Guideline n (valid %) |
Non-guideline n (valid %) |
p-value |
|---|---|---|---|
| General factors | |||
| Size of hospital | |||
| Large (n = 998) | 870 (87.2) | 128 (12.8) | < 0.01 |
| Medium (n = 467) | 261 (55.9) | 206 (44.1) | |
| Small (n = 61) | 41 (66.2) | 20 (32.8) | |
| NePeriQIP triala | |||
| Baseline (n = 467) | 326 (69.8) | 141 (30.2) | < 0.01 |
| Intervention (n = 970) | 769 (79.3) | 201 (20.7) | |
| Born at home | 62 (6.5) | 20 (6.1) | 0.81 |
| Inborn infants | 719 (82.3) | 211 (66.7) | < 0.01 |
| Maternal factors | |||
| Maternal age in years, mean (SD) | 24.5 (4.8) | 24.8 (0.27) | 0.27 |
| Disadvantaged casteb | 276 (23.6) | 58 (16.4) | < 0.01 |
| Caesarean section (elective & emergency) | 47 (4.3) | 21 (6.1) | 0.16 |
| Infant factors | |||
| Admission weight, mean (SD) | 2820 (612) | 2841 (636) | 0.58 |
| Gestational age, mean (SD) | 38.5 (2.7) | 38.9 (2.9) | 0.06 |
| Apgar 5 min < 7 | 53 (8.8) | 16 (7.7) | 0.64 |
| Outcome (death or referral to higher centre) | 96 (8.4) | 39 (11.3) | 0.10 |
Missing data: Intervention (n = 89); Born at home (n = 242); Inborn (n = 336); Caesarean section (n = 89); Admission weight (n = 31); Gestational age (n = 616); Apgar 5 min (n = 716); Outcome (n = 39).
aNepal Perinatal Quality Improvement Project
bDalit and Muslim