Table 4.
A—NYU |
Non-progressors JSN ≤ 0 mm (n = 39) Mean (SD) |
Fast progressors JSN ≥ 0.5 mm (n = 45) Mean (SD) |
p value | FDR |
Cartilage medial overall (0–30) | 13.88 (8.61) | 15.42 (8.71) | 0.42 | 0.42 |
Cartilage lateral overall (0–30) | 3.56 (6.62) | 5.24 (7.89) | 0.298 | 0.398 |
BML medial overall (0–15) | 0.59 (1.14) | 1.78 (2.22) | 0.003 | 0.014 |
BML lateral overall (0–15) | 0.33 (0.80) | 0.16 (0.47) | 0.214 | 0.398 |
B—OAI |
Non-progressors JSN ≤ 0 mm (n = 29) Mean (SD) |
Fast progressors JSN ≥ 0.5 mm (n = 34) Mean (SD) |
p value | FDR |
Cartilage loss medial (0–36) | 4.21 (2.90) | 7.09 (3.78) | 0.006 | 0.014 |
Cartilage loss lateral (0–36) | 5.04 (4.09) | 2.32 (2.80) | 0.012 | 0.025 |
BML medial overall (0–36) | 1.21 (1.82) | 3.27 (2.31) | 0.002 | 0.013 |
BML lateral overall (0–36) | 2.23 (2.84) | 0.98 (1.50) | 0.072 | 0.102 |
Abbreviations: WORMS Whole-Organ Magnetic Resonance Imaging Score, BML bone marrow lesion, JSN joint space narrowing, FDR false discovery rate. JSN values are expressed in mm as mean ± standard deviation (SD). All comparisons are versus non-progressors (JSN ≤ 0 mm). Significant p values are represented in bold font