Table 3.
Features and findings of treadmill exercise Cardiac MRI studies in coronary artery disease
Study | Patient population | n. | Mean Age (years) |
Treadmill location | Findings |
---|---|---|---|---|---|
Rerkpattanapipat (2003) [33] |
Patients referred for coronary angiography | 27 | 62 ± 11 | Outside scanner room | Detected coronary artery stenosis > 70% on coronary angiography with sensitivity and specificity of 79% & 85%. |
Raman (2010) [31] | Patients referred for SPECT | 43 | 54 ± 12 | MR scanner room corner | Exercise stress CMR is feasible with cine wall motion and perfusion assessment and has moderate agreement with SPECT (K = 0.58) |
Sukpraphrute (2015) [43] | Patients with known or suspected CAD | 115 | 59 ± 13 | Outside scanner room | Treadmill Ex-CMR RWMA assessment identified those at risk of future adverse events (myocardial infarction, death, unstable angina prompting admission) 47% with RWMA vs 17% without |
Raman (EXACT trial) (2016) [45] |
Patients referred for SPECT | 94 | 59 ± 13 | Scanner adjacent | Treadmill stress CMR demonstrated a stronger correlation with coronary angiography and superior specificity, sensitivity, positive and negative predictive values for > 70% stenosis at angiography than treadmill SPECT |
Abbreviations: CAD coronary artery disease, CMR cardiovascular magnetic resonance, RWMA regional wall motion abnormality, SPECT single photon emission computed tomography,