Table 2.
Relationship between clinical features of pancreatic cancer and the miR-221-3p content determined by RT-qPCR
| Characteristics | N | M ± SD | p |
|---|---|---|---|
| Tissues | |||
| Adjacent non-cancerous tissues | 16 | 9.603 ± 1.129 | < 0.0001* |
| Pancreatic cancer | 16 | 12.422 ± 1.147 | |
| Age (years) | |||
| < 60 | 5 | 12.87 ± 1.040 | 0.3038 |
| ≥ 60 | 11 | 12.22 ± 1.179 | |
| Gender | |||
| Male | 8 | 12.40 ± 1.202 | 0.9533 |
| Female | 8 | 12.44 ± 1.172 | |
| Tumor size(cm) | |||
| ≤3 | 6 | 12.10 ± 0.902 | 0.4093 |
| >3 | 10 | 12.61 ± 1.278 | |
| smoke | |||
| No | 11 | 12.58 ± 1.217 | 0.4346 |
| Yes | 5 | 12.08 ± 1.007 | |
| Lymphatic Metastasis | |||
| No | 7 | 12.06 ± 1.070 | 0.2834 |
| Yes | 9 | 12.70 ± 1.186 | |
| Vital status | |||
| Live | 3 | 11.61 ± 0.037 | 0.1832 |
| Death | 13 | 12.61 ± 1.201 | |
| Stage | |||
| Stage I–II | 8 | 12.81 ± 1.337 | 0.1836 |
| Stage III–IV | 8 | 12.03 ± ±0.827 | |
| Vascular invasion | |||
| No | 5 | 12.77 ± 1.360 | 0.4338 |
| Yes | 11 | 12.26 ± 1.070 | |
| Histological type | |||
| Pancreatic ductal adenocarcinoma | 15 | 12.482 ± 1.160 | 0.0061* |
| Undifferentiated cancer | 1 | 11.516 | |
| Nerve invasion | |||
| No | 2 | 12.92 ± 1.905 | 0.528 |
| Yes | 14 | 12.35 ± 1.093 | |
| Diabetes | |||
| No | 13 | 12.04 ± 0.850 | 0.0016* |
| Yes | 3 | 14.09 ± 0.617 | |
N indicates number, SD indicates standard deviation, M indicates mean, *indicates significant difference defined as p < 0.05