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. 2020 Jul 28;202(1):106–118. doi: 10.1111/cei.13485

Fig. 2.

Fig. 2

Flow cytometry analyses of inducible co‐stimulator (ICOS)+ programmed cell death protein 1 (PD‐1)+ follicular helper T cells (Tfh) cells in ulcerative colitis (UC) patients. (a) Representative dot‐plots of peripheral ICOS+PD‐1+ Tfh cells in active UC patients, stable remission UC patients and healthy controls (HCs). Fluorescence minus one (FMO) scatter‐plots for ICOS or PD‐1 are shown as controls. Numbers indicates the corresponding percentages of ICOS+PD‐1+ subsets within CD4+CXCR5+forkhead box protein 3 (FoxP3)− Tfh cells. (b) Comparison of ICOS+PD‐1+ Tfh cell percentages and absolute numbers (per liter) in active UC patients (n = 34), stable remission UC patients (n = 34) and healthy controls (n = 34). Data are shown as mean with standard deviation (s.d.). ***P < 0·001; *P < 0·05; n.s. = not significant.