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. 2020 Jul 28;202(1):106–118. doi: 10.1111/cei.13485

Table 2.

The efficacy of Tfh subsets in distinguishing active UC from stable remission UC patients

AUC Cut‐off value (%) Sensitivity Specificity
ICOS+PD‐1+ Tfh 0·883 2·48 81·9 89·1
ICOS+ Tfh 0·722 3·43 71·3 62·9
PD‐1+ Tfh 0·728 11·8 81·2 59·2
ICOS+PD‐1+ Tfh plus PD‐1+ Tfh 0·931 2·53 + 11·4 86·3 89·1
ICOS+PD‐1+ Tfh plus ICOS+ Tfh 0·826 2·60 + 3·38 81·7 84·2
ICOS+ Tfh plus PD‐1+ Tfh 0·832 3·51 + 11·8 82·9 83·8

AUC = area under the receiver operating characteristic (ROC) curve; ICOS = inducible co‐stimulator; PD‐1 = programmed cell death protein 1; Tfh = follicular helper T cells; UC = ulcerative colitis.