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. 2020 Sep 9;26:86. doi: 10.1186/s10020-020-00201-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — The effects of THRIL on AKT pathway and autophagy pathway were reversed through knockdown of FUS. (a) and (b) AKT signaling pathway expressions in various transfection groups. (c) and (d) ATG1 and LC3-II expression levels in various transfection groups. NC: EPCs isolated from CAD patients; All the transfection experiments were performed in EPCs isolated from CAD patients. *P < 0.05, compared with NC group. The data shown represent three separate experiments performed in triplicate in each experiment (mean ± the standard deviation [SD])