Table 1.

Experimental product.

	Probiotic	Placebo
General content	Probiotic Streptococcus dentisani CECT 7746 + Excipients	Excipients without probiotic
Vial composition	-2.5 × 109 CFUs/vial - 2% (p/v) Guar gum - 6% (p/v) hydroxyethylcellulose	-2% (p/v) Guar gum - 6% (p/v) hydroxyethylcellulose
Probiotic dose	2.5 × 109 CFUs/vial Administration every 48 h, equivalent to 1010 CFUs/week	–
Route of administration	Topic application in the mouth	Topic application in the mouth
Galenic form	Buccoadhesive gel	Buccoadhesive gel

Probiotic and placebo composition.