Table 1.
Demographic and Clinical Characteristics of Participants
| All subjects (n = 179) | GAD without comorbid affective disorder (n = 100) | GAD with comorbid affective disorder (n = 79) | pa | |
|---|---|---|---|---|
| Age (mean/SD) | 45.7 ± 15.3 | 44.7 ± 16.5 | 46.9 ± 13.5 | 0.32 |
| Gender (N, %) | 0.26 | |||
| Male | 60 (34) | 30 (30) | 30 (38) | |
| Female | 119 (66) | 70 (70) | 49 (62) | |
| Age GAD onset (mean/SD) | 21.5 ± 15.4 | 18.6 ± 14.1 | 25.1 ± 16.2 | 0.0045 |
| Episode length (years) (mean/SD) | 8.4 ± 13.9 | 10.1 ± 16.1 | 6.2 ± 10.1 | 0.081 |
| HRSA total (mean/SD) | 14.7 ± 3.6 | 14.2 ± 3.3 | 15.5 ± 3.8 | 0.012 |
| GAD-7 (mean/SD) | 13.7 ± 2.8 | 13.3 ± 2.6 | 14.2 ± 2.9 | 0.029 |
| Age depression onset (mean/SD) | 23.6 ± 14.5 | 20.4 ± 11.1 | 25.7 ± 16.1 | 0.089 |
| HRSD 17 total (mean/SD) | 13.7 ± 4.0 | 12.3 ± 3.4 | 15.5 ± 3.9 | <0.001 |
| HRSD total (mean/SD) | 16.5 ± 5.5 | 14.3 ± 4.5 | 19.3 ± 5.4 | <0.001 |
| HRSD core scoreb (mean/SD) | 2.2 ± 1.5 | 1.7 ± 1.2 | 2.9 ± 1.6 | <0.001 |
| HRSD extended core scorec (mean/SD) | 5.0 ± 2.5 | 4.0 ± 2.1 | 6.3 ± 2.4 | <0.001 |
| BDI total (mean/SD) | 19.5 ± 10.1 | 16.0 ± 8.1 | 23.9 ± 10.7 | <0.001 |
| BAI total (mean/SD) | 16.8 ± 9.4 | 16.2 ± 9.5 | 17.6 ± 9.2 | 0.33 |
All statistical tests were two-sided. Bold indicates statistical significance set at 0.05.
a
Chi-square or two-sample t-test p values.
b
Item 1, 2, and 3.
c
Item 1, 2, 3, 7, 8, and 13.
BAI, Beck anxiety inventory; BDI, Beck depression inventory; GAD, generalized anxiety disorder; HRSD, Hamilton rating scale for depression; SD, standard deviation.