Table 3.
Comparison of clinical characteristics in survival and non-survival groups in 52 children with P. aeruginosa bacteremia
| Characteristics | Non-survival (n = 12) |
Survival (n = 40) |
P values |
|---|---|---|---|
| Basic information | |||
| Age(years) (median, IQR) | 1.55(0.21–9.80) | 1.79(0.44–9.01) | 0.373 |
| Male (n, %) | 8(66.7%) | 24(60.0%) | 0.938 |
| Weight (kilogram) (median, IQR) | 10.00(4.85–29.88) | 11.25(7.00–27.00) | 0.521 |
| Underlying diseases | |||
| Hematologic malignancies (n, %) | 2(16.7%) | 14(35.0%) | 0.395 |
| Congenital heart disease (n, %) | 1(8.3%) | 6(12.5%) | 1.000 |
| Underlying conditions | |||
| Immunosuppression (n, %) | 5(41.7%) | 21(52.5%) | 0.743 |
| Neutropenia (n, %) | 8(66.7%) | 16(40.0%) | 0.195 |
| Hypoalbuminemia (n, %) | 9(75.0%) | 13(32.5%) | 0.023* |
| Complications | |||
| Pneumonia (n, %) | 3(25.0%) | 6(15.0%) | 0.129 |
| Meningitis (n, %) | 2(16.7%) | 3(7.5%) | 0.699 |
| Peritonitis (n, %) | 0(0.0%) | 3(7.5%) | 0.333 |
| Origins of infection | |||
| Respiratory tract (n, %) | 6(50.0%) | 16(40.0%) | 0.740 |
| Primary bacteremia (n, %) | 1(8.3%) | 6(15.0%) | 0.911 |
| Vascular-catheter related infection (n, %) | 1(8.3%) | 7(17.5%) | 0.752 |
| Soft tissue infection (n, %) | 3(25.3%) | 5(12.5%) | 0.551 |
| Gastrointestinal infection (n, %) | 1(8.3%) | 4(10.0%) | 1.000 |
| Post-surgery or-procedure bacteremia (n, %) | 0(0.0%) | 2(5.0%) | 0.434 |
| Intensive unit care (n, %) | 6(50.0%) | 14(35.0%) | 0.500 |
| Nosocomial infection (n, %) | 4(33.3%) | 18(45.0%) | 0.701 |
| Pittsburgh bacteremia scores (median, IQR) | 4.50(1.25–7.25) | 1.00(1.00–3.75) | 0.043* |
| Antibiotics administration before blood culture (n, %) | 7(58.3%) | 24(60.0%) | 1.000 |
| Inappropriate empirical antimicrobial therapy (n, %) | 5(41.7%) | 9(22.5%) | 0.267 |
| TTP (median, IQR) | 15.19(11.21–18.24) | 19.42(16.92–20.97) | 0.005* |
| Length of hospitalization days (median, IQR) | 2.86(2.07–28.08) | 26.44(19.80–44.63) | 0.002* |
| Multi-drug resistance bacteria (n, %) | 0(0.0%) | 4(10.0%) | 0.259 |
| Septic shock (n, %) | 7(58.3%) | 8(20.0%) | 0.025* |
* Indicates statistical significant results, P<0.05