Table 3.
The list of 36 best North Eurasian SNPs for eye color prediction
| SNP_ID | Caucasus Score | European Russia Score | West Siberia Score | Pooled Dataset Score | HIrisPlex-S | dbSNP RSID | Gene |
|---|---|---|---|---|---|---|---|
| chr15:28356859_C_T | 2 | 2 | 2 | 3 | rs1129038 | rs1129038 | HERC2 |
| chr15:28365618_A_G | 2 | 2 | 2 | 3 | rs12913832 | rs12913832;4745 | HERC2 |
| chr15:28392261_G_A | 2 | 2 | 3 | rs12898729 | HERC2 | ||
| chr15:28410491_C_T | 2 | 2 | 3 | rs12916300 | HERC2 | ||
| chr15:28495956_A_G | 2 | 2 | 3 | rs12912427 | HERC2 | ||
| chr15:28562998_T_C | 1 | 2 | rs1614575 | HERC2 | |||
| chr20:39272620_A_G | 1 | 2 | rs4812447 | Intergene spacer | |||
| chr1:119406130_C_T | 2 | rs1779446 | Intergene spacer | ||||
| chr1:3331899_A_G | 2 | rs1999528 | PRDM16 | ||||
| chr15:28145024_T_C | 2 | rs2871886 | OCA2 | ||||
| chr15:28364059_A_G | 2 | rs7494942 | HERC2 | ||||
| chr15:28380518_T_A | 2 | rs4778249 | HERC2 | ||||
| chr15:28383565_T_C | 2 | rs7403279 | HERC2 | ||||
| chr15:28513364_T_C | 2 | rs916977;4744 | HERC2 | ||||
| chr15:28530182_C_T | 2 | rs1667394 | rs1667394;4743 | HERC2 | |||
| chr15:28566122_A_G | 2 | rs751089833 | HERC2 | ||||
| chr19:7570978_T_C | 2 | rs685034 | C19orf45 | ||||
| chr3:189429301_G_T | 2 | rs6804480 | TP63 | ||||
| chr6:45136347_G_A | 2 | rs1324530 | SUPT3H | ||||
| chrX:66405249_C_T | 2 | rs34191540 | Intergene spacer | ||||
| chr10:87576467_C_T | 1 | rs7923503 | GRID1 | ||||
| chr14:92909309_T_C | 1 | rs12588868 | SLC24A4 | ||||
| chr15:28419048_T_G | 1 | rs35946704 | HERC2 | ||||
| chr17:9107969_G_A | 1 | rs17742781 | NTN1 | ||||
| chr19:7578733_A_T | 1 | rs586243 | ZNF358 | ||||
| chr3:189552236_T_C | 1 | rs7653443 | MIR944 | ||||
| chr3:33035542_T_C | 1 | rs4586761 | GLB1 | ||||
| chr3:33111182_T_G | 1 | rs72856153 | GLB1 | ||||
| chr3:54251172_G_A | 1 | rs11283625 | CACNA2D3 | ||||
| chr3:54636061_G_A | 1 | rs34983676 | CACNA2D3 | ||||
| chr4:87847613_T_G | 1 | 1 | rs10022539 | LOC100506746 | |||
| chr4:87851083_C_T | 1 | rs72667724 | LOC100506746 | ||||
| chr5:60947483_A_G | 1 | rs1501841 | C5orf64 | ||||
| chr5:73959526_A_G | 1 | rs2454846 | HEXB | ||||
| chr6:45419110_C_G | 1 | rs2820339 | RUNX2 | ||||
| chr7:42032565_C_T | 1 | rs2237427 | GLI3 |
Indicated in bold - new SNPs which demonstrated the high prediction power for the eye color
Columns: SNP_ID – SNP ID in format: chromosome:position in GRCh37_allele 1_allele 2. Caucasus score, European Russia Score, West Siberia Score, Pooled Dataset Score – scores as described in section “Eye color prediction” for corresponding datasets
HIrisPlex-S – RS ID if used in HIrisPlex-S. Otherwise empty
dbSNP RSID – RS ID in dbSNP database
Gene – Nearest gene for this SNP