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. 2020 Aug 4;11(9):1694–1703. doi: 10.1021/acsmedchemlett.0c00126

Figure 2.

Figure 2

Molecular structure of Rho-kinase isoform and its sequences. It consists of three domains, N-terminus entailed catalytic site of an enzyme, followed by a coiled-coil region comprising the Rho-binding domain. C-terminal is a Pleckstrin-homology (PH) with an internal cysteine-rich domain (CRD). (Chem Draw Ultra Version 12.0, http://www.CambridgeSoft.com).